史庆华个人简历

史庆华，男，1964年出生于江苏徐州，博士，中国科学技术大学教授、博士生导师，国家杰出青年基金获得者、科技部重大科学研究计划专家组专家。

1998年毕业于南京师范大学，获博士学位。

1992年10月-1993年11月德国国立环境与健康研究中心访问学者。

1996年10月-1997年12月作为联合培养博士生在德国国立环境与健康研究中心(GSF-National Research Center for Environment and Health, Germany)学习。

1998年11月－2001年12月加拿大卡加里大学(University of Calgary, Canada)博士后。

2002年1月－2004年12月哈佛大学医学院(Harvard Medical School, USA)Research Fellow。

2004年入选中国科学院“引进国外杰出人才”项目，同年12月全职全时回国，现为中国科技大学合肥微尺度物质科学国家实验室PI(Principal Investigator)和生命科学学院教授、博士生导师。

2005年7月通过中科院”百人计划”择优支持。

工作以来共发表研究论文30余篇,已作为第一或联系作者在Nature、Am J Hum Genet(影响因子12.34) 等SCI杂志上发表论文11篇，被他引200余次；在2005年，论文被引用80余次。

担任《PloS One》、《遗传》、《中国细胞生物学报》和《生命科学》等多家杂志的常务编委或编委。作为第一或通讯作者在Nature、American Journal of Human Genetics、Human Genetics、Cell Cycle、Bioinformatics和Cell Research等杂志上发表SCI论文30余篇，被他人引用1000余次。

中国科学院“百人计划”启动经费课题、国家自然科学基金项目

1、分子细胞遗传学/肿瘤染色体异常的发生途径

2、生殖生物学/配子发生的遗传调控

1) Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. - NATURE - 200510 - 437:1038－1042

2) Absence of age effect on meiotic recombination between human X and Y chromosomes - AMERICAN JOURNAL OF HUMAN GENETICS - 2002 - 71(2):254-261

3) Lagging chromosomes entrapped in micronuclei are notu2018lostu2019by cells - Cell Research - 201202 - 2012

4) Recurrent trisomy and Robertsonian translocation of chromosome 14 in murine iPS cell lines - Chromosome Research - 201110 - 19(7):857-68

5) Complex relationship between meiotic recombination frequency and autosomal synaptonemal complex length per cell in normal human males - American Journal of Medical Genetics - 201202 - Epub ahead of print

6) Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries - PLoS One - 201101 - 6(1):e16046

7) Prediction of novel pre-microRNAs with high accuracy through boosting and SVM - Bioinformatics - 201103 - 27(10):1436-1437

8) The fate of micronucleated cells post X-irradiation detected by live cell imaging - DNA Repair (Amst) - 201103 - 10:629-638

9) Multiple origins of spontaneously arising micronuclei in HeLa cells: Direct evidence from long-term live cell imaging - MUTATION RESEARCH - 200811 - 646(1-2):41-49

10) Abnormal synapsis and recombination in an azoospermic male carrier of a reciprocal translocation t(1;21). - FERTILITY AND STERILITY - 200902 - 91(4):1293 e17-22

11) Cryopreservation has no effect on meiotic recombination and synapsis in testicular tissues - FERTILITY AND STERILITY - 200808 - 91(4):1404-7

12) Cigarette smoking and aneuploidy in human sperm - MOLECULAR REPRODUCTION AND DEVELOPMENT - 200108 - 59(4):417-421

13) Recombination in the pseudoautosomal region in a 47, XYY male - HUMAN GENETICS - 200108 - 109(2):143-145

14) Increased nondisjunction of chromosome 21 with age in human peripheral lymphocytes - MUTATION RESEARCH - 200007 - 452(1):27-36

15) Incidence of mosaic cell lines in vivo and malsegregation of chromosome 21 in lymphocytes in vitro of trisomy 21 patients: detection by fluorescence in situ hybridization on binucleated lymphocytes - HUMAN GENETICS - 200001 - 106(1):29-35

16) Aneuploidy in human spermatozoa: FISH analysis in men with constitutional chromosomal abnormalities, and in infertile men - REPRODUCTION - 200105 - 121(5):655-666

17) Single sperm typing demonstrates that reduced recombination is associated with the production of aneuploid 24,XY human sperm - AMERICAN JOURNAL OF MEDICAL GENETICS - 200102 - 99(1):34-38

18) Multicolor fluorescence in situ hybridization analysis of meiotic chromosome segregation in a 47,XYY male and a review of the literature - AMERICAN JOURNAL OF MEDICAL GENETICS - 200007 - 936(1):40-46

19) Spontaneous frequencies of aneuploid and diploid sperm in 10 normal Chinese men: assessed by multicolor fluorescence in situ hybridization - CYTOGENETICS AND CELL GENETICS - 2000 - 90(1-2):79-83

20) Aneuploidy in human sperm: a review of the frequency and distribution of aneuploidy, effects of donor age and lifestyle factors - CYTOGENETICS AND CELL GENETICS - 2000 - 90(3-4):219-226

21) The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells - J Clin Invest - 200912 - 119(12):3626-36

22) Comparative proteome profile of immature rat ovary during primordial follicle assembly and development - Proteomics - 200907 - 9(13):3425-34

23) Nucleophosmin/B23 inhibits Eg5-mediated microtubule depolymerization by inactivating its ATPase activity - J Biol Chem - 201006 - 285(25):19060-7