如何以编程方式禁用系统设备？

看起来drf版本中有两件事给您带来麻烦。您的x64问题是由SP_DEVINFO_DATA的uint需要IntPtr引起的。第二个问题是SetupDiGetDevicePropertyW函数是Vista
+，不会在XP上运行。

这是修正了这两个问题的版本。我在XPx86和Win7X64上测试了x86和AnyCPU。

public static class DisableHardware{    const uint DIF_PROPERTYCHANGE = 0x12;    const uint DICS_ENABLE = 1;    const uint DICS_DISABLE = 2;  // disable device    const uint DICS_FLAG_GLOBAL = 1; // not profile-specific    const uint DIGCF_ALLCLASSES = 4;    const uint DIGCF_PRESENT = 2;    const uint ERROR_INVALID_DATA = 13;    const uint ERROR_NO_MORE_ITEMS = 259;    const uint ERROR_ELEMENT_NOT_FOUND = 1168;    static DEVPROPKEY DEVPKEY_Device_DeviceDesc;    static DEVPROPKEY DEVPKEY_Device_HardwareIds;    [StructLayout(LayoutKind.Sequential)]    struct SP_CLASSINSTALL_HEADER    {        public UInt32 cbSize;        public UInt32 InstallFunction;    }    [StructLayout(LayoutKind.Sequential)]    struct SP_PROPCHANGE_PARAMS    {        public SP_CLASSINSTALL_HEADER ClassInstallHeader;        public UInt32 StateChange;        public UInt32 Scope;        public UInt32 HwProfile;    }    [StructLayout(LayoutKind.Sequential)]    struct SP_DEVINFO_DATA    {        public UInt32 cbSize;        public Guid classGuid;        public UInt32 devInst;        public IntPtr reserved;     // CHANGE #1 - was UInt32    }    [StructLayout(LayoutKind.Sequential)]    struct DEVPROPKEY    {        public Guid fmtid;        public UInt32 pid;    }    [Dllimport("setupapi.dll", SetLastError = true)]    static extern IntPtr SetupDiGetClassDevsW(        [In] ref Guid ClassGuid,        [MarshalAs(UnmanagedType.LPWStr)]string Enumerator,        IntPtr parent,        UInt32 flags);    [Dllimport("setupapi.dll", SetLastError = true)]    static extern bool SetupDiDestroyDeviceInfoList(IntPtr handle);    [Dllimport("setupapi.dll", SetLastError = true)]    static extern bool SetupDiEnumDeviceInfo(IntPtr deviceInfoSet,        UInt32 memberIndex,        [Out] out SP_DEVINFO_DATA deviceInfoData);    [Dllimport("setupapi.dll", SetLastError = true)]    static extern bool SetupDiSetClassInstallParams(        IntPtr deviceInfoSet,        [In] ref SP_DEVINFO_DATA deviceInfoData,        [In] ref SP_PROPCHANGE_PARAMS classInstallParams,        UInt32 ClassInstallParamsSize);    [Dllimport("setupapi.dll", SetLastError = true)]    static extern bool SetupDiChangeState(        IntPtr deviceInfoSet,        [In] ref SP_DEVINFO_DATA deviceInfoData);    [Dllimport("setupapi.dll", SetLastError = true)]    static extern bool SetupDiGetDevicePropertyW( IntPtr deviceInfoSet, [In] ref SP_DEVINFO_DATA DeviceInfoData, [In] ref DEVPROPKEY propertyKey, [Out] out UInt32 propertyType, IntPtr propertyBuffer, UInt32 propertyBufferSize, out UInt32 requiredSize, UInt32 flags);    [Dllimport("setupapi.dll", SetLastError = true)]    static extern bool SetupDiGetDeviceRegistryPropertyW(      IntPtr DeviceInfoSet,      [In] ref SP_DEVINFO_DATA  DeviceInfoData,      UInt32 Property,      [Out] out UInt32  PropertyRegDataType,      IntPtr PropertyBuffer,      UInt32 PropertyBufferSize,      [In,Out] ref UInt32 RequiredSize    );    static DisableHardware()    {        DisableHardware.DEVPKEY_Device_DeviceDesc = new DEVPROPKEY();        DEVPKEY_Device_DeviceDesc.fmtid = new Guid(     0xa45c254e, 0xdf1c, 0x4efd, 0x80, 0x20, 0x67,     0xd1, 0x46, 0xa8, 0x50, 0xe0);        DEVPKEY_Device_DeviceDesc.pid = 2;        DEVPKEY_Device_HardwareIds = new DEVPROPKEY();        DEVPKEY_Device_HardwareIds.fmtid = new Guid( 0xa45c254e, 0xdf1c, 0x4efd, 0x80, 0x20, 0x67, 0xd1, 0x46, 0xa8, 0x50, 0xe0);        DEVPKEY_Device_HardwareIds.pid = 3;    }    public static void DisableDevice(Func<string, bool> filter, bool disable = true)    {        IntPtr info = IntPtr.Zero;        Guid NullGuid = Guid.Empty;        try        { info = SetupDiGetClassDevsW(     ref NullGuid,     null,     IntPtr.Zero,     DIGCF_ALLCLASSES); CheckError("SetupDiGetClassDevs"); SP_DEVINFO_DATA devdata = new SP_DEVINFO_DATA(); devdata.cbSize = (UInt32)Marshal.SizeOf(devdata); // Get first device matching device criterion. for (uint i = 0; ; i++) {     SetupDiEnumDeviceInfo(info,         i,         out devdata);     // if no items match filter, throw     if (Marshal.GetLastWin32Error() == ERROR_NO_MORE_ITEMS)         CheckError("No device found matching filter.", 0xcffff);     CheckError("SetupDiEnumDeviceInfo");     string devicepath = GetStringPropertyForDevice(info,          devdata, 1); // SPDRP_HARDWAREID     // Uncomment to print name/path     //Console.WriteLine(GetStringPropertyForDevice(info,     //   devdata, DEVPKEY_Device_DeviceDesc));     //Console.WriteLine("   {0}", devicepath);     if (devicepath != null && filter(devicepath)) break; } SP_CLASSINSTALL_HEADER header = new SP_CLASSINSTALL_HEADER(); header.cbSize = (UInt32)Marshal.SizeOf(header); header.InstallFunction = DIF_PROPERTYCHANGE; SP_PROPCHANGE_PARAMS propchangeparams = new SP_PROPCHANGE_PARAMS(); propchangeparams.ClassInstallHeader = header; propchangeparams.StateChange = disable ? DICS_DISABLE : DICS_ENABLE; propchangeparams.Scope = DICS_FLAG_GLOBAL; propchangeparams.HwProfile = 0; SetupDiSetClassInstallParams(info,     ref devdata,     ref propchangeparams,     (UInt32)Marshal.SizeOf(propchangeparams)); CheckError("SetupDiSetClassInstallParams"); SetupDiChangeState(     info,     ref devdata); CheckError("SetupDiChangeState");        }        finally        { if (info != IntPtr.Zero)     SetupDiDestroyDeviceInfoList(info);        }    }    private static void CheckError(string message, int lasterror = -1)    {        int pre = lasterror == -1 ? Marshal.GetLastWin32Error() : lasterror;        if (pre != 0) throw new ApplicationException(     String.Format("Error disabling hardware device (Code {0}): {1}",         pre, message));    }    private static string GetStringPropertyForDevice(IntPtr info, SP_DEVINFO_DATA devdata,        uint propId)    {        uint proptype, outsize;        IntPtr buffer = IntPtr.Zero;        try        { uint buflen = 512; buffer = Marshal.AllocHGlobal((int)buflen); outsize=0; // CHANGE #2 - Use this instead of SetupDiGetDeviceProperty  SetupDiGetDeviceRegistryPropertyW(     info,     ref devdata,     propId,     out proptype,     buffer,     buflen,     ref outsize); byte[] lbuffer = new byte[outsize]; Marshal.Copy(buffer, lbuffer, 0, (int)outsize); int errpre = Marshal.GetLastWin32Error(); if (errpre == ERROR_INVALID_DATA) return null; CheckError("SetupDiGetDeviceProperty", errpre); return Encoding.Unipre.GetString(lbuffer);        }        finally        { if (buffer != IntPtr.Zero)     Marshal.FreeHGlobal(buffer);        }    }}